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Methotrexate â Side-Effects, Safety and Recall Information

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... study shows Methotrexate to be most popularly prescribed disease modifying anti-rheumatic drug ...  more

According to the FDA's data, Methotrexate®* side-effects are common and include:

· thinned or brittle hair
· blistering skin or acne
· loss of appetite or weight

Tell your doctor if either of these side-effects is severe or lasts for several hours:

· mouth blistering
· fatigue
If you experience any of the following side-effects, call your doctor immediately:

· painful urination or red urine
· black, tarry stools
· unusual bruising or bleeding
· congestion
· fever
· dizziness
· chills
· shortness of breath
· sore throat
· swelling of the feet or ankles
· vomiting
· pain in the joints
· seizures
· severe skin rash


*Methotrexate® is marketed by various manufacturers as an anti-metabolite used for the treatment of cancer, severe psoriasis, and adult rheumatoid arthritis.


Disclaimer: The information presented here is not meant to be medical advice nor to act as a substitute for medical advice. Serious side-effects, including death, could result if one were to take any prescription medicine without the supervision of a physician.

Copyright 2003, Thomas Manaugh, PhD